European Chemical Biology Library Extension

Beschreibung der Beschaffung

EU-OPENSCREEN (EU-OS) is a European Research Infrastructure Consortium (ERIC). It provides world-class services to academia and industry in the fields of small molecule screening and medicinal chemistry. Thereby, it promotes the rich chemical knowledge of Europe and enables systematic studies of a larger collection of compounds leading to novel insights into cellular and organismal metabolic and signaling pathways.

EU-OS hosts in its facilities the European Chemical Biology Library (ECBL). ECBL is defined as a general-purpose screening library and is used by the screening platforms that are affiliated with the EU-OS research infrastructure. Its current size is 100’000 compounds and shall now be extended by various sub-libraries of different compound classes and design principles. For each of these sub-libraries, the EU-OPENSCREEN consortium has compiled lists with desired compound structures.
Each of the sub-libraries corresponds to a different lot that is awarded to a vendor.

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Lot 1:
- Name: Diversity
- Minimum number of compounds: 5000
- Maximum price: 200000 €
- Annex file: Annex_Lot1_Diversity.csv

The annex file "Annex_Lot1_Diversity.csv" contains a group column depicting the scaffold. Only one compound out of each group number must be offered.

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Further details can be found in the tender documents.

Beschreibung der Beschaffung

EU-OPENSCREEN (EU-OS) is a European Research Infrastructure Consortium (ERIC). It provides world-class services to academia and industry in the fields of small molecule screening and medicinal chemistry. Thereby, it promotes the rich chemical knowledge of Europe and enables systematic studies of a larger collection of compounds leading to novel insights into cellular and organismal metabolic and signaling pathways.

EU-OS hosts in its facilities the European Chemical Biology Library (ECBL). ECBL is defined as a general-purpose screening library and is used by the screening platforms that are affiliated with the EU-OS research infrastructure. Its current size is 100’000 compounds and shall now be extended by various sub-libraries of different compound classes and design principles. For each of these sub-libraries, the EU-OPENSCREEN consortium has compiled lists with desired compound structures.
Each of the sub-libraries corresponds to a different lot that is awarded to a vendor.

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Lot 2:
- Name: RNA Binders
- Minimum number of compounds: 1800
- Maximum price: 72000 €
- Annex file: Annex_Lot2_RNABinders.csv

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Further details can be found in the tender documents.

Beschreibung der Beschaffung

EU-OPENSCREEN (EU-OS) is a European Research Infrastructure Consortium (ERIC). It provides world-class services to academia and industry in the fields of small molecule screening and medicinal chemistry. Thereby, it promotes the rich chemical knowledge of Europe and enables systematic studies of a larger collection of compounds leading to novel insights into cellular and organismal metabolic and signaling pathways.

EU-OS hosts in its facilities the European Chemical Biology Library (ECBL). ECBL is defined as a general-purpose screening library and is used by the screening platforms that are affiliated with the EU-OS research infrastructure. Its current size is 100’000 compounds and shall now be extended by various sub-libraries of different compound classes and design principles. For each of these sub-libraries, the EU-OPENSCREEN consortium has compiled lists with desired compound structures.
Each of the sub-libraries corresponds to a different lot that is awarded to a vendor.

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Lot 3:
- Name: Chemogenomics1
- Minimum number of compounds: 450
- Maximum price: 90000 €
- Annex file: Annex_Lot3_Chemogenomics1.csv

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Further details can be found in the tender documents.

Beschreibung der Beschaffung

EU-OPENSCREEN (EU-OS) is a European Research Infrastructure Consortium (ERIC). It provides world-class services to academia and industry in the fields of small molecule screening and medicinal chemistry. Thereby, it promotes the rich chemical knowledge of Europe and enables systematic studies of a larger collection of compounds leading to novel insights into cellular and organismal metabolic and signaling pathways.

EU-OS hosts in its facilities the European Chemical Biology Library (ECBL). ECBL is defined as a general-purpose screening library and is used by the screening platforms that are affiliated with the EU-OS research infrastructure. Its current size is 100’000 compounds and shall now be extended by various sub-libraries of different compound classes and design principles. For each of these sub-libraries, the EU-OPENSCREEN consortium has compiled lists with desired compound structures.
Each of the sub-libraries corresponds to a different lot that is awarded to a vendor.

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Lot 4:
- Name: Chemogenomics2
- Minimum number of compounds: 100
- Maximum price: 20000 €
- Annex file: Annex_Lot4_Chemogenomics2.csv

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Further details can be found in the tender documents.

Beschreibung der Beschaffung

EU-OPENSCREEN (EU-OS) is a European Research Infrastructure Consortium (ERIC). It provides world-class services to academia and industry in the fields of small molecule screening and medicinal chemistry. Thereby, it promotes the rich chemical knowledge of Europe and enables systematic studies of a larger collection of compounds leading to novel insights into cellular and organismal metabolic and signaling pathways.

EU-OS hosts in its facilities the European Chemical Biology Library (ECBL). ECBL is defined as a general-purpose screening library and is used by the screening platforms that are affiliated with the EU-OS research infrastructure. Its current size is 100’000 compounds and shall now be extended by various sub-libraries of different compound classes and design principles. For each of these sub-libraries, the EU-OPENSCREEN consortium has compiled lists with desired compound structures.
Each of the sub-libraries corresponds to a different lot that is awarded to a vendor.

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Lot 5:
- Name: PROTAC
- Minimum number of compounds: 88
- Maximum price: 132000 €
- Annex file: Annex_Lot5_PROTAC.csv

The annex file "Annex_Lot5_PROTAC.csv" contains a group column depicting the target. Only a maximum of 40 compounds out of each group number must be offered.

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Further details can be found in the tender documents.

Beschreibung der Beschaffung

EU-OPENSCREEN (EU-OS) is a European Research Infrastructure Consortium (ERIC). It provides world-class services to academia and industry in the fields of small molecule screening and medicinal chemistry. Thereby, it promotes the rich chemical knowledge of Europe and enables systematic studies of a larger collection of compounds leading to novel insights into cellular and organismal metabolic and signaling pathways.

EU-OS hosts in its facilities the European Chemical Biology Library (ECBL). ECBL is defined as a general-purpose screening library and is used by the screening platforms that are affiliated with the EU-OS research infrastructure. Its current size is 100’000 compounds and shall now be extended by various sub-libraries of different compound classes and design principles. For each of these sub-libraries, the EU-OPENSCREEN consortium has compiled lists with desired compound structures.
Each of the sub-libraries corresponds to a different lot that is awarded to a vendor.

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Lot 6:
- Name: MolecularGlueDegradersE3
- Minimum number of compounds: 50
- Maximum price: 15000 €
- Annex file: Annex_Lot6_MolecularGlueDegradersE3.csv

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Further details can be found in the tender documents.

Liste und kurze Beschreibung der Regeln und Kriterien

Extract from Trade Register or Certificate of Registration and Description of Business Activities:

Extract from Trade Register (copy) (if the tenderer has an entry) or alternatively a comparable Certificate of Registration and Description of Business Activities.

Direct Link to Questionaire for qualification verification:

https://tender-portal.com/NetServer/SelectionCriteria/54321-Tender-1985004bda9-6ae51fa906b2b5e0

Liste und kurze Beschreibung der Regeln und Kriterien

Economic and Financial Standing - Annual Turnover - Minimum Requirement:

Annual Turnover and the annual Turnover within the area covered by the contract is and we confirm that we have not intentionally made false statements during the procurement procedure concerning our eligibility.

The Minimum Average Turnover in Compound Libraries within the last three completed financial years for each Lot is defined as follows:

- Lot 1 - Diversity: 400,000 €
- Lot 2 - RNA Binders: 144,000 €
- Lot 3 - Chemogenomics1: 180,000 €
- Lot 4 - Chemogenomics2: 40,000 €
- Lot 5 - PROTAC: 264,000 €
- Lot 6 - MolecularGlueDegradersE3: 30,000 €

Direct Link to Questionaire for qualification verification:

https://tender-portal.com/NetServer/SelectionCriteria/54321-Tender-1985004bda9-6ae51fa906b2b5e0

Liste und kurze Beschreibung der Regeln und Kriterien

Technical and Professional Ability - List of References:

List of References (supply contracts concerning comparable Compound Libraries)

The commencement of contract has to date back at least 1 year and maximal 3 years from the deadline for submission of bids/tenders.

The following information must be provided for each reference:
- Recipient
- Net order value
- Date/Period of Performance
- Description

Direct Link to Questionaire for qualification verification:

https://tender-portal.com/NetServer/SelectionCriteria/54321-Tender-1985004bda9-6ae51fa906b2b5e0

Tenders/Bids are submitted exclusively electronically via the tendering platform
https://tender-portal.com/

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There, the tender documents must be opened, processed and submitted using the AI Biddingcockpit after the bidders have registered on the platform free of charge.
Tenders must be submitted electronically. Only receipt by the contracting authority is decisive for the receipt of tenders in time. It should be noted that problems may occur when uploading bids. Bidders are therefore required to start the upload process in good time so that any problems can be resolved.

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Questions about the documents or the procurement procedure must be submitted exclusively via AI Biddingcockpit. The questions received in good time will be checked by the contracting authority and then answered anonymously to all bidders via the tender platform. Information is not provided by telephone.

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Information and FAQs on using the AI Biddingcockpit can be found at the following link:
https://www.bietercockpit.de/faq.html

Genaue Informationen über Fristen für Überprüfungsverfahren

Section 160 Competition Act (Gesetz gegen Wettbewerbsbeschränkungen - GWB):
Initiation of the Proceedings, Application

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(1) The public procurement tribunal shall initiate review proceedings only upon application.

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(2) Every undertaking that has an interest in the public contract or the concession and claims that its rights under Section 97(6) have been violated by non-compliance with the provisions governing the awarding of public contracts has the right to file an application. In doing so, the undertaking must show that it has been or risks being harmed by the alleged violation of public procurement provisions.

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(3) The application is inadmissible if
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1. the applicant became aware of the claimed violation of public procurement provisions before filing the application for review, but did not complain to the contracting authority within a time limit of 10 calendar days; the expiry of the time limit under Section 134(2) remains unaffected,
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2. violations of public procurement provisions which become apparent from the tender notice are not notified to the contracting authority by the end of the time limit for the application or the submission of a tender specified in the notice,
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3. violations of public procurement provisions which only become apparent from the procurement documents are not notified to the contracting authority by the end of the time limit for the application or the submission of a tender specified in the notice,
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4. more than 15 calendar days have expired since receipt of notification from the contracting entity that it is unwilling to redress the objection.

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Sentence 1 shall not apply to an application under Section 135(1) no 2 to have the contract declared ineffective. Section 134(1) sentence 2 shall remain unaffected.

Genaue Informationen über Fristen für Überprüfungsverfahren

Section 160 Competition Act (Gesetz gegen Wettbewerbsbeschränkungen - GWB):
Initiation of the Proceedings, Application

---
(1) The public procurement tribunal shall initiate review proceedings only upon application.

---
(2) Every undertaking that has an interest in the public contract or the concession and claims that its rights under Section 97(6) have been violated by non-compliance with the provisions governing the awarding of public contracts has the right to file an application. In doing so, the undertaking must show that it has been or risks being harmed by the alleged violation of public procurement provisions.

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(3) The application is inadmissible if
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1. the applicant became aware of the claimed violation of public procurement provisions before filing the application for review, but did not complain to the contracting authority within a time limit of 10 calendar days; the expiry of the time limit under Section 134(2) remains unaffected,
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2. violations of public procurement provisions which become apparent from the tender notice are not notified to the contracting authority by the end of the time limit for the application or the submission of a tender specified in the notice,
---
3. violations of public procurement provisions which only become apparent from the procurement documents are not notified to the contracting authority by the end of the time limit for the application or the submission of a tender specified in the notice,
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4. more than 15 calendar days have expired since receipt of notification from the contracting entity that it is unwilling to redress the objection.
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Sentence 1 shall not apply to an application under Section 135(1) no 2 to have the contract declared ineffective. Section 134(1) sentence 2 shall remain unaffected.


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Section 135 Competition Act (Gesetz gegen Wettbewerbsbeschränkungen - GWB):
Ineffectiveness

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(1) A public contract shall be deemed ineffective from the outset if the public contracting authority
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1. has violated Section 134 or
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2. has awarded the contract without prior publication or announcement in the Official Journal of the European Union without this being expressly permissible in accordance with the law and this violation has been ascertained in review proceedings.

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(2) Ineffectiveness pursuant to subsection (1) can be established only if this is claimed in review proceedings within 30 calendar days after the public contracting authority informs the affected candidates and tenderers concerning the conclusion of the contract, but at the latest six months after conclusion of the contract. If the contracting authority has published the award of the contract in the Official Journal of the European Union, the time limit for claiming ineffectiveness shall end 30 calendar days after publication of the notice of the award in the Official Journal of the European Union.

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(3) Ineffectiveness under subsection (1) no 2 shall not arise where
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1. the public contracting authority holds the view that it is permissible to award the contract without prior publication of an announcement in the Official Journal of the European Union;
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2. the public contracting authority has published an announcement in the Official Journal of the European Union, in which it expresses its intention to conclude the contract; and
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3. the contract was not concluded before the expiry of a period of at least 10 calendar days from the day of publication of that announcement.
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The announcement according to sentence 1 no 2 must include the name and contact data of the public contracting authority, the description of the contract subject matter, the justification for the decision of the contracting authority to award the contract without prior publication of an announcement in the Official Journal of the European Union, and the name and contact data of the undertaking that is to be awarded the contract.